“Our brother Robert, who became our brother Alexis, who became our sister Alexis, passed this morning September 11, at 12:23am,” her brother Richmond wrote on Facebook.
“He was surrounded by all of his brothers and sisters, one of his nieces and several other loves ones. We were playing music for him and he passed during David Bowie’s ‘Starman.’
"As per his wishes, we cheered at the moment that he transitioned to another dimension.”
People have reported that her cause of death was due to "complications related to AIDS".
Arquette, who was born a male, transitioned to female in 2006, which was the subject of a documentary titled Alexis Arquette: She’s My Brother.