"Humbled to be the first Asian, Indian to win Mr.world 2016," Khandelwal said after his win.
"Lots of love to all who have been supporting and following my journey. I can't express how much I have been motivated from every message I see.. Love you all.
"My journey has been a journey of transformation and I give entire credit to people I crossed my path with who only helped me to become a better human being."
The 12-day competition saw contestants compete in events ranging from physical capabilities to fashion sense, and of course there was a talent component.
Winners were selected by a judging panel combined with votes from the public.
Khandelwal worked as a technical support assistant in Hyderabad, India before moving to Mumbai to study business and pursue his dream of acting and modeling.