Tyler rose to fame for his iconic depiction of Central Perk's resident café manager. While his role was low-key, he remained a fixture throughout all 10 seasons of Friends.
Perhaps most notable for his crush on Rachel Green (played by Jennifer Aniston), the actor garnered a big fan base and became just as synonymous with the show as its six main actors.
Tyler had previously said of his experience on the show: "It was the most memorable 10 years of my life... I could not have imagined just a better experience. All these guys were fantastic and just a joy to work with. It felt very, very special."
In recent years, Tyler continued acting—even throughout his cancer treatment.
His last project were The Gesture and the Word, and Processing, both of which he earned critical acclaim for.
Our thoughts are with his family at this difficult time.