Sandra Bullock and Melissa McCarthy
These two played the hilarious crime-fighting cop duo in The Heat. They have been described as “inseparable”, even off-screen.
Daniel Radcliffe and Rupert Grint
Harry Potter and his best friend Ron Weasley stole our hearts from the time they ran together through the brick wall to get to Platform 9¾.
Kristen Wiig and Maya Rudolph
Ever since their SNL days, Kristen and Maya have been a comedy match made in heaven. Fans rejoiced when their film Bridesmaids hit cinemas.
Will Ferrell and John C. Reilly
This fun-loving pair have appeared together in multiple films, but it was in Step Brothers that their bromance truly blossomed.
Amy Poehler and Tina Fey
When these real-life BFFs join forces, it’s nothing short of comedic gold. Their chemistry shined in Sisters.
Owen Wilson and Vince Vaughn
Two key members of the ‘90s "Frat Pack", Owen Wilson and Vince Vaughn get along so well onscreen it’s little surprise the two have a close friendship in real life too.
Drew Barrymore and Cameron Diaz
These two Hollywood angels met as teens in LA, and friendship blossomed on the set of Charlie’s Angels. More recently, Cam has publicly supported Drew during her divorce.
Brad Pitt and George Clooney
We first saw sparks fly between these two dreamboats when they co-starred in Ocean’s Eleven in 2001, and the two have appeared in many more award-winning films since. Off-screen, the pair is frequently spotted together, reportedly playing pranks on each other, in true bromance fashion.
Ben Affleck and Matt Damon
Both native Bostonians, Ben Affleck and Matt Damon have been friends since childhood. This gifted pair even wrote Good Will Hunting together and took home Oscars for the film.
James Franco and Seth Rogen
From Pineapple Express to The Interview and that hilarious spoof of Kanye West’s Bound 2, Franco and Rogen together are one of Hollywood’s most entertaining bromances.
Wilson and Tom Hanks
In one of the most heart wrenching Hollywood moments, we watched with tears in our eyes as these two friends bonded and were torn apart at sea in Castaway.