6 Peptide Serums For Plump, Youthful-Looking Skin

The gentle alternative to potent anti-ageing ingredients.
Imaan Hammam

If you have access to the Internet, then you’ve probably been swept up in the wave that is peptide skin care.

Popularised by Hailey Bieber and her glazed skin, fans looking to emulate the star’s glossy visage clamoured to secure Rhode Skin’s Peptide Glazing Fluid when it launched in June 2022. But for those of us who live in Australia (AKA outside of Rhode’s shipping territory), we’ve been relegated to hunting our local beauty retailers and department stores for peptide serums that deliver the same plump, youthful-looking finish.

Thankfully, we didn’t have to search too hard, because there are plenty of equally impressive serums available down under that feature the gentle anti-ageing ingredient alongside a slew of supporting superstars like hyaluronic acid, niacinamide, panthenol, squalane, amino acids and the list goes on. Used on the daily, these peptide serums work to reinforce proteins in the skin like collagen and elastin to help visibly plump and firm the skin, as well as smooth visible fine lines and wrinkles.

Down to try this buzzworthy skin care ingredient? Ahead, marie claire rounds up the best peptide serums to shop in Australia.

2024’s top 3 peptide serums

  1. Estée Lauder Advanced Night Repair Synchronized Multi-Recovery Complex, $135, Adore Beauty
  2. The Ordinary Multi-Peptide + HA Serum, $29.90, Adore Beauty
  3. Go-To Skincare Much Plumper Skin, $48, Go-To Skincare

The best peptide serums 2024


Estée Lauder Advanced Night Repair Synchronized Multi-Recovery Complex

from $135 at Adore Beauty

Best for: Better beauty sleep

Tripeptide-32 is the hero ingredient in this gentle, night-time serum, it helps to reinforce and strengthen the skin’s natural repair process, which happens while you sleep. And when you wake up, expect to see an improvement in your skin’s firmness, radiance, tone and wrinkles.

Sizes: 30ml / 50ml / 75ml

Key features:

  • Features tripeptide-32 and hyaluronic acid
  • Reinforces the skin’s natural repair process
  • Improves firmness, tone, radiance and wrinkles
  • Non-comedogenic
  • Free from synthetic fragrance

Available at:


The Ordinary Multi-Peptide + HA Serum

from $29.90 at Adore Beauty

Best for: Sticking to your budget

Injecting a peptide serum into your skincare routine doesn’t have to impact your budget. This pick from The Ordinary features a buffet of peptides, hyaluronic acid, and amino acids, which work in unison to address the first signs of ageing and a lack of hydration.

Sizes: 30ml / 60ml

Key features:

  • Contains four types of peptides (SYN™-AKE, Matrixyl™ synthe’6™, Matrixyl™ 3000, and ARGIRELOX™ peptide)
  • Enriched with hyaluronic acid, amino acids, and bio-derivatives
  • Addresses the first signs of ageing
  • Helps to hydrate skin
  • Improves elasticity and firmness
  • Smooths visible signs of crow’s feet

Available at:


Go-To Skincare Much Plumper Skin

from $48 at Go-To Skincare

Best for: Dehydrated skin

With four types of hydrating hyaluronic acid, soothing aloe vera juice and provitamin B5, and plumping acetyl hexapeptide-8, this serum from Go-To is the thirst-quencher your skin has been waiting for.

Sizes: 30ml

Key features:

  • Contains acetyl hexapeptide-8, aloe vera, provitamin B5 and four types of hyaluronic acid
  • Hydrates skin and seals in moisture
  • Plumps, smooths and firms
  • Prevents trans epidermal water loss
  • Lightweight and fragrance-free

Available at:


Medik8 Liquid Peptides

$110 at Adore Beauty

Best for: The no-nonsense approach

With a potent 30 per cent peptide complex, Medik8’s Liquid Peptides isn’t holding anything back when it comes to reinforcing the skin’s processes for stronger skin that stands up to the visible signs of ageing.

Sizes: 30ml

Key features:

  • Contains drone-targeted copper peptide, MATRIXYL™ 3000, carnosine, expression line peptide, hyaluronic acid and prebiotics
  • Minimises the appearance of premature skin ageing
  • Fades visible signs of fine lines and wrinkles
  • Refines skin texture and tone
  • Plumps and firms

Available at:


Biossance Squalane and Copper Peptide Rapid Plumping Serum

from $125 at Sephora

Best for: Bouncy plumpness

Boasting a mixture of moisturising squalane, hyaluronic acid and polyglutamic acid, this pick from Biossance helps to plump and hydrate skin both instantly and over time for a bouncy, youthful-looking complexion.

Sizes: 12ml / 50ml

Key features:

  • Infused with a rapid plumping complex (squalane, hyaluronic acid and polyglutamic acid)
  • Contains collagen boosting copper peptides
  • Paracress extract lifts and firms skin
    Keeps skin hydrated and moisturised
  • Promotes a bouncy, plump and youthful-looking complexion

Available at:


Paula’s Choice Pro-Collagen Multi-Peptide Booster

$89 at Paula’s Choice

Best for: Versatility

Paula’s Choice created this booster serum to deliver potent quantities of peptides to the skin. It can be used solo, layered, or mixed with other serums or a moisturiser to enhance an existing skin care routine. It also comes in a smaller “travel size” 5ml version for $28 – great if you’re going away or want to try it out first.

Sizes: 5ml / 20ml

Key features:

  • Contains six repairing pro-collagen peptides, hydrating hyaluronic acid and strengthening amino acids
    Supports and improves the appearance of skin
  • Enhances firmness and plumpness
  • Smooths visible signs of fine lines and wrinkles
  • Can be mixed into other serums and moisturiser

Available at:

What does a peptide serum do?

Peptides are short chains of amino acids that are the building blocks of certain proteins needed by the skin (read: collagen and elastin). Using a peptide serum can help to firm and plump skin, and smooth fine lines, for a more youthful-looking complexion.

Is peptide serum better than hyaluronic acid?

Peptides and hyaluronic acid are complementary skin care ingredients that work well together, however it’s tough to compare the two ingredients as they have different properties. Both ingredients can plump and smooth fine lines, but they don’t do this in the same way. Hyaluronic acid temporarily draws moisture into the skin to plump and hydrate, while peptides reinforce proteins in the skin.

Looking to save money on a peptide serum? Check out our coupon codes for MECCA, Sephora and more.

Related article:

Main image credit: @imaanhammam

Related stories